Telmisartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in a number of tissues.
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Telmicos® H is a combination of an angiotensin II receptor antagonist, Telmisartan, and a thiazide diuretic, Hydrochlorothiazide. The combination of these ingredients has an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alone.
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Dapagliflozin mechanism of action is to inhibit the glucose transporter (SGLT2) in the renal tubule, thus reducing resorption of glucose by this transporter, with the consequent reduced blood glucose.Metformin is a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycaemia
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