Vildagliptin a high affinity (DPP-4) inhibitor enhances insulin secretion via augmented incretin effect. The administration of vildagliptin results in a rapid and complete inhibition of DPP-4 activity, resulting in increased fasting and postprandial endogenous levels of the incretin hormones GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide).
Glucowell-Met combines two antihyperglycaemic agents with complimentary mechanisms of action to improve glycemic control in patients with type 2 diabetes: Vildagliptin, a member of the islet enhancer class, and Metformin hydrochloride, a member of the Biguanide class.