Cosmos Pharmaceutical Limited | FLUCOLD®Capsule
Cosmos Limited is one of the leading manufacturers of pharmaceutical products in Kenya and East Africa. Through our specialized Human Health and Animal Health.
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FLUCOLD®Capsule

CLINICAL PHARMACOLOGY:

Dextromethorphan Hydrobromide is a cough suppressant used for the relief of non-productive cough; it has a central action on the cough centre in the medulla.
Triprolidine Hydrochloride, an alkylamine derivative, is a sedating antihistamine with antimuscarinic and mild sedative effects.
Phenylephrine hydrochloride is a sympathomimetic amine which  acts on alpha adrenergic receptors or the respiratory tract to produce vasoconstriction, which temporarily reduces the swelling associated with inflammation of the mucous membranes lining the nasal and sinus passages. This allows the free drainage of the sinusoidal fluid from the sinuses. It also supresses the production of mucus, therefore preventing a build up of fluid within the cavities.
Ibuprofen, a propionic acid derivative, is an NSAID used in the management of mild to moderate pain and fever.
‘Ascorbic Acid (coated) Vitamin C’, a water-soluble vitamin, is essential for the synthesis of collagen and intercellular material.

Pharmacokinetics:

Dextromethorphan is rapidly absorbed from the gastro-intestinal tract. It is metabolised in the liver and excreted as unchanged dextromethorphan and demethylated metabolites.
After absorption from the gastro-intestinal tract, Triprolidine is metabolised; a carboxylated derivative accounts for about half the dose excreted in the urine. Reported half-lives vary from 3-5 hours or more.
Phenylephrine Hydrochloride is readily absorbed after oral administration but is subject to extensive presystemic metabolism. It has a mean plasma half-life in the range of 2-3 hours.Following absorption, the drug is extensively biotransformed in the liver and both phenylephrine hydrochloride and its metabolites are excreted in urine. It is excreted in breast milk, but no harm should come to neonate if intake is not excessive.

FLUCOLD®  CAPSULES

Ibuprofen is absorbed from the gastro-intestinal tract and peak plasma concentrations occur about 1 to 2 hours after ingestion. It is rapidly excreted in the urine mainly as metabolites and their conjugates. There appears to be little if any distribution into breast milk.
Vitamin C (Ascorbic Acid) is readily absorbed from the gastro-intestinal tract and is widely distributed in the body tissues. It is excreted in the urine. Ascorbic Acid crosses the placenta and is distributed into breast milk. It is removed by haemodialysis.

USES:

Flucold® Capsule provides a convenient and effective way to relieve major cold and flu symptoms. Flucold® helps to clear a blocked or runny nose and to relieve sneezing, aches, pains and fever. Flucold® also helps to ease a cough.

DOSAGE   AND  ADMINISTRATION:

Adults and Children, 12 years and over: One capsule  every 4-6 hours a day as required preferably with or after food. Do not exceed 6 capsules in any 24 hours.
Not suitable for children under 12 years.

CONTRA-INDICATIONS AND WARNINGS:
Precautions:

Do not exceed the stated dose.
This medicine may cause drowsiness. If affected, do not drive or operate machinery. Avoid alcohol when taking this preparation. Do not take this medicine if you have a stomach ulcer or are sensitive to Aspirin.
If you are currently taking any other medication, consult your pharmacist or doctor before using this product.
If symptoms persist for more than 72 hours, then consult your doctor.

Pregnancy: Not recommended.

PHARMACEUTICAL  PRECAUTIONS:

Store in a dry place below 25°C. Protect from light. Keep all medicines out of the reach of children.

LEGAL  CATEGORY:
Pharmacy (P)
®Regd. TM                                       Ref. No.: INS310/05.11

IMAGES
  • FLUCOLD®Capsules

    PresentationWhite crystalline powder filled in blue/maroon hard gelatin capsule printed 'COSMOS / FLUCOLD' on body and cap. .Pack size - 100's (10x10's)